In all chronic diseases death is produced by the same cause, namely, the chemical action of the atmosphere. When those substances are wanting, whose function in the organism is to support the process of respiration, when the diseased organs are incapable of performing their proper function of producing these substances, when they have lost the power of transforming the food into that shape in which it may, by entering into combination with the oxygen of the air, protect the system from its influence, then, the substance of the organs themselves, the fat of the body, the substance of the muscles, the nerves, and the brain, are unavoidably consumed. The true cause of death in these cases is the respiratory process, that is, the action of the atmosphere. A deficiency of food, and a want of power to convert the food into a part of the organism, are both, equally, a want of resistance; and this is the negative cause of the cessation of the vital process. The flame is extinguished, because the oil is consumed; and it is the oxygen of the air which has consumed it. In many diseases substances are produced which are incapable of assimilation. By the mere deprivation of food, these substances are removed from the body without leaving a trace behind; their elements have entered into combination with the oxygen of the air. From the first moment that the function of the lungs or of the skin is interrupted or disturbed, compounds, rich in carbon, appear in the urine, which acquires a brown colour. Over the whole surface of the body oxygen is absorbed, and combines with all the substances which offer no resistance to it. In those parts of the body where the access of oxygen is impeded; for example, in the arm-pits, or in the soles of the feet, peculiar compounds are given out, recognisable by their appearance, or by their odour. These compounds contain much carbon. Respiration is the falling weight--the bent spring, which keeps the clock in motion; the inspirations and expirations are the strokes of the pendulum which regulate it. In our ordinary time-pieces, we know with mathematical accuracy the effect produced on their rate of going, by changes in the length of the pendulum, or in the external temperature. Few, however, have a clear conception of the influence of air and temperature on the health of the human body; and yet the research into the conditions necessary to keep it in the normal state is not more difficult than in the case of a clock. LETTER VIII My dear Sir, Having attempted in my last letter to explain to you the simple and admirable office subserved by the oxygen of the atmosphere in its combination with carbon in the animal body, I will now proceed to present you with some remarks upon those materials which sustain its mechanisms in motion, and keep up their various functions,--namely, the Aliments.