Professor Henry Carrington Bolton, in the _Popular Science Monthly_ for January and February, 1896, relates this incident of Smithson: "It is said that he frequently narrated an anecdote of himself which illustrated his remarkable skill in analyzing minute quantities of substances, an ability which rivalled that of Dr. Wollaston. Happening to observe a tear gliding down a lady's cheek, he endeavored to catch it on a crystal vessel. One-half the tear-drop escaped; but he subjected the other half to reagents, and detected what was then called microcosmic salt, muriate of soda, and some other saline constituents held in solution." When Mr. Smithson was over fifty years of age, in 1818 or 1819, he had a misunderstanding with the Royal Society, owing to their refusal to publish one of his papers. It is said that prior to this he intended to leave all his wealth, over $500,000 to the society. About three years before his death, he made a brief will, giving the income of his fortune to his nephew, Henry James Hungerford, and the whole fortune to the children of his nephew, if he should marry. In case he did not marry, Smithson bequeathed the whole of his property "to the United States of America, to found at Washington, under the name of the Smithsonian Institution, an establishment for the increase and diffusion of knowledge among men." Mr. Smithson, says Professor Simon Newcomb, "is not known to have had the personal acquaintance of an American, and his tastes were supposed to have been aristocratic rather than democratic. We thus have the curious spectacle of a retired English gentleman bequeathing the whole of his large fortune to our Government, to found an establishment which was described in ten words, without a memorandum of any kind by which his intentions could be divined, or the recipient of the gift guided in applying it." Mr. Smithson died June 27, 1829, in Genoa, Italy, at the age of sixty-four. His nephew survived him only six years, dying unmarried at Pisa, Italy, June 5, 1835. He used the income from his uncle's estate while he lived, and upon his death it passed to the United States. Hungerford's mother, who had married a Frenchman, Madame Théodore de la Batut, claimed a life-interest in the estate of Smithson, which was granted till her death in 1861. To meet this annuity $26,210 was retained in England until she died. For several years it was difficult to decide in what way Congress should use the money "for the increase and diffusion of knowledge among men." John Quincy Adams desired a great astronomical observatory; Rufus Choate of Massachusetts urged a grand library; a senator from Ohio wished a botanical garden; another person a college for women; another a school for indigent children of the District of Columbia; still another a great agricultural school.