Only the third week after the prince’s death, Galileo felt the first effects of his heavy loss. In a letter of 24th August, Castelli urgently advised him “for many most weighty reasons which he did not wish just then to commit to paper, to have the work printed at Florence, and as soon as possible.”[231] Castelli added that he had inquired of Father Visconti whether this would present any difficulties, to which he had replied that there was nothing to prevent, and he (Visconti) desired above all things that the work should see the light. Galileo was the more ready to fall in with this proposition because the plague, which had made fearful ravages in North Italy, had now made its appearance in Tuscany, and the precautionary measures taken by the neighbouring States made all intercourse with them, and especially with the States of the Church, very tedious and often impossible. Galileo therefore at once took the needful steps for publishing his book at Florence. He applied to the Inquisitor-General of the city, to the Vicar-General, and to the political authorities for permission, and it was granted without hesitation on 11th September, 1630.[232] Galileo next addressed himself to Riccardi; represented to him the great obstacles to publishing the work at Rome, and therefore asked permission to publish it at Florence. This was the beginning of troubles. The chief of the Roman censorship at first roundly refused, and when Galileo urged his request again, he informed him through the Tuscan ambassador at the papal court, Francesco Niccolini, that the work must be sent in for final revision as agreed upon, without which he should never have consented to the publication. Castelli also wrote to Galileo on 21st September,[233] as commissioned by Riccardi, that as his coming himself to Rome, as originally agreed upon, was rendered impossible by the outbreak of the plague, he had better send the manuscript to Riccardi, in order that he and Mgr. Ciampoli might make the final corrections. Castelli said further that Riccardi was still very favourably disposed to Galileo, and that when his work had undergone this censorship, he could send it to press in Florence as well as anywhere else. After this Galileo made inquiries whether, under present circumstances, a large packet of MSS. could be sent safely over the border. But he was everywhere met with a negative, and the remark that mere letters scarcely passed. In vain he applied to the postmaster, in vain he appealed to the Grand Ducal secretary of state, Bali Cioli, for help; no means could be devised, under the strict close of the frontiers, whereby the bulky work could be transmitted to Rome with any prospect of safety.