Prayer of Hon. and Rev. Baptist Noel--Residence in Cambridgeshire-- Visit to London in 1861, and first attendance at Barnet Conferences-- Visit of Rev. W. and Mrs. Pennefather--East of London, 1861--Left Cambridgeshire, 1865--Work in Bedford Institute--1866: Voyage to New York and return, 1867--First girl rescued--Matchbox makers--First boy rescued--Revival Refuge open for boys and girls--1868: Home of Industry secured--1869: Opened. The winter of 1860-61 is a time to be had much in remembrance before the Lord. It was then that the East of London, with all its sins and sorrows, was laid as a heavy, burden on the heart of His faithful and beloved servant Reginald Radcliffe. Before the commencement of his labours, a few Christian friends met for prayer at the invitation of the Hon. and Rev. Baptist Noel. The East of London, and its "stunning-tide of human care and crime," was not the only thought of that revered man of God. His faith looked forward to greater things, and one well-remembered petition was, that blessing through the work then to be begun in that deeply degraded and neglected region, might not be stayed there, but might flow from thence to far-off lands. One then present, the Dowager Lady Rowley, was not long permitted to sow precious seed with her own hand, but was instrumental in the fulfilment of this petition, as it was through her leading that Miss Macpherson's voice was first heard in the East of London. At that time Miss Macpherson was residing in the neighbourhood of Cambridge with her sister and brother-in-law, Mr. Merry, and, was already a worker in the Lord's vineyard. She thus writes of the year 1861:-- "It was a turning point in my life. I made a pilgrimage to London to attend the preaching of Reginald Radcliffe in the City of London Theatre, Shoreditch. There I met Dr. Elwin. On the following evening, at the Young Men's Christian Association, Great Marlborough Street, he introduced me to Lady Rowley, Mr. Morgan, and many other Christian friends. Through them I was led to attend the next Barnet Conference, where I learned what it was to wait for the coming of the Lord." With this bright and blessed hope she returned to work with a strength and power before unknown. Many souls had already been awakened, but the full tide of blessing had not yet come. In the villages around her hundreds of labourers were employed in digging for coprolites, a fossil which, when ground, is useful as manure. Among these men were many of the wildest wanderers, and Miss Macpherson's heart was deeply stirred for their spiritual welfare, and her time and strength were given to reach them by every means in her power. She had established evening schools, lending libraries and coffee-sheds, and of these and further efforts she wrote:--