Lastly, the brain and spinal cord, and all the nervous matter, become, under the influence of alcohol, subject alike to organic deterioration. "The membranes enveloping the nervous substance undergo thickening; the blood-vessels are subjected to change of structure, by which their resistance and resiliency is impaired; and the true nervous matter is sometimes modified, by softening or shrinking of its texture, by degeneration of its cellular structure or by interposition of fatty particles. These deteriorations of cerebral and spinal matter give rise to a series of derangements, which show themselves in the worst forms of nervous diseases--epilepsy; paralysis, local or general; insanity." We have quoted thus largely from Dr. Richardson's valuable lectures, in order that our readers may have an intelligent comprehension of this most important subject. It is because the great mass of the people are ignorant of the real character of the effects produced on the body by alcohol that so many indulge in its use, and lay the foundation for troublesome, and often painful and fatal diseases in their later years. In corroboration of Dr. Richardson's testimony against alcohol, we will, in closing this chapter, make a few quotations from other medical authorities. FARTHER MEDICAL TESTIMONY. Dr. Ezra M. Hunt says: "The capacity of the alcohols for impairment of functions and the initiation and promotion of organic lesions in vital parts, is unsurpassed by any record in the whole range of medicine. _The facts as to this are so indisputable, and so far granted by the profession, as to be no longer debatable_. Changes in stomach and liver, in kidneys and lungs, in the blood-vessels to the minutest capillary, and in the blood to the smallest red and white blood disc disturbances of secretion, fibroid and fatty degenerations in almost every organ, impairment of muscular power, impressions so profound on both nervous systems as to be often toxic--these, and such as these, are the oft manifested results. And these are not confined to those called intemperate." Professor Youmans says: "It is evident that, so far from being the conservator of health, alcohol is an active and powerful cause of disease, interfering, as it does, with the respiration, the circulation and the nutrition; now, is any other result possible?" Dr. F.R. Lees says: "That alcohol should contribute to the fattening process under certain conditions, and produce in drinkers fatty degeneration of the blood, follows, as a matter of course, since, on the one hand, we have an agent that _retains waste_ matter by lowering the nutritive and excretory functions, and on the other, a _direct poisoner_ of the vesicles of the vital stream."