"The _destructive_ effects of alcohol on the human mind present, finally, the saddest picture of its influence. The most æsthetic artist can find no angel here. All is animal, and animal of the worst type. Memory irretrievably lost, words and very elements of speech forgotten or words displaced to have no meaning in them. Rage and anger persistent and mischievous, or remittent and impotent. Fear at every corner of life, distrust on every side, grief merged into blank despair, hopelessness into permanent melancholy. Surely no Pandemonium that ever poet dreamt of could equal that which would exist if all the drunkards of the world were driven into one mortal sphere. [Illustration: CRAZED BY DRINK. "God's rational offspring ... become a brute."] "As I have moved among those who are physically stricken with alcohol, and have detected under the various disguises of name the fatal diseases, the pains and penalties it imposes on the body, the picture has been sufficiently cruel. But even that picture pales, as I conjure up, without any stretch of imagination, the devastations which the same agent inflicts on the mind. Forty per cent., the learned Superintendent of Colney Hatch, Dr. Sheppard, tells us, of those who were brought into that asylum in 1876, were so brought because of the direct or indirect effects of alcohol. If the facts of all the asylums were collected with equal care, the same tale would, I fear, be told. What need we further to show the destructive action on the human mind? The Pandemonium of drunkards; the grand transformation scene of that pantomime of drink which commences with, moderation! Let it never more be forgotten by those who love their fellow-men until, through their efforts, it is closed forever." We might go on, adding page after page of evidence, showing how alcohol curses the souls, as well as the bodies, of men; but enough has been educed to force conviction on the mind of every reader not already satisfied of its poisonous and destructive quality. How light are all evils flowing from intemperance compared with those which it thus inflicts on man's higher nature. "What," says Dr. W.E. Channing, "is the great essential evil of intemperance? The reply is given, when I say, that intemperance is the "VOLUNTARY EXTINCTION OF REASON.