Although the poisonous symptoms of tobacco are, in a great degree, the same in different persons at the inception of the habit, the effects vary materially in after years according to the quantity and variety used, the form employed and the habits and temperament of the user. One man will chew a paper a week, another four, many use one a day, and a few from one and a half to three a day, besides smoking. Occasionally, but very rarely, we find a man who limits himself to one cigar a day, a number allow themselves but three, but of later years even these are moderate compared with those who use eight, ten or more. There are many men who, for years, preserve a robust, hale appearance under both tobacco and whisky, who are, notwithstanding their apparent health, steadily laying the foundation of diseased heart, or DERANGEMENT OF THE DIGESTIVE ORGANS or nervous system from the former, or an organic fatal disease of the liver or kidneys from the latter. Healthy-looking men are often rejected by examiners of life insurance companies because of irregular and intermittent action of the heart from tobacco; and equally robust subjects are forced to abandon the habit because of tremors, vertigo or a peculiar form of dyspepsia. We have known men who died from the use of tobacco, and others who met a like fate from whisky, who were never fully in the state denominated drunk. Men may earn a hobnail liver and dropsy by the constant, steady use of alcoholic drink taken systematically, so as always to keep within the limits of intoxication; or they may, in the same way, get a diabetes or Bright's disease. Abundant testimony in regard to the effects of tobacco in creating an appetite for strong drink has been given by the inmates of the Franklin Home. In a few exceptional cases the use of tobacco does not appear to create any sense of thirst; and this is specially the case with the smokers who do not spit when smoking. Some men seem to be free from any alcoholic craving when using tobacco, and say that when they commence to drink they give up the drug for the time being. These are exceptional cases, for excess in drinking generally leads to an excess in the use of tobacco, often to double the amount ordinarily employed. We have often been told by moderate drinkers, that they frequently FELT A DESIRE FOR A LITTLE WHISKY AFTER A SMOKE,