I trust, Mr. President, that you—whom untoward circumstances have made a biologist, but who still keep alive your sympathy with that class of inquiries which nature intended you to pursue and adorn—will excuse me to your brethren if I say that some of them seem to form an inadequate estimate of the distance which separates the microscopic from the molecular limit, and that, as a consequence, they sometimes employ a phraseology which is calculated to mislead. When, for example, the contents of a cell are described as perfectly homogeneous, as absolutely structureless, because the microscope fails to distinguish any structure, then I think the microscope begins to play a mischievous part. A little consideration will make it plain to all of you that the microscope can have no voice in the real question of germ structure. Distilled water is more perfectly homogeneous than the contents of any possible organic germ. What causes the liquid to cease contracting at 39° F., and to grow bigger until it freezes? It is a structural process of which the microscope can take no note, nor is it likely to do so by any conceivable extension of its powers. Place this distilled water in the field of an electro-magnet, and bring a microscope to bear upon it. Will any change be observed when the magnet is excited? Absolutely none; and still profound and complex changes have occurred. First of all, the particles of water are rendered diamagnetically polar; and secondly, in virtue of the structure impressed upon it by the magnetic strain of its molecules, the liquid twists a ray of light in a fashion perfectly determinate both as to quantity and direction. It would be immensely interesting to both you and me if one here present, who has brought his brilliant imagination to bear upon this subject, could make us see as he sees the entangled molecular processes involved in the rotation of the plane of polarization by magnetic force. While dealing with this question he lived in a world of matter and of motion to which the microscope has no passport, and in which it can offer no aid. The cases in which similar conditions hold are simply numberless. Have the diamond, the amethyst, and the countless other crystals formed in the laboratories of nature and of man, no structure? Assuredly they have, but what can the microscope make of it? Nothing. It cannot be too distinctly borne in mind that between the microscopic limit and the true molecular limit there is room for infinite permutations and combinations. It is in this region that the poles of the atoms are arranged, that tendency is given to their powers, so that when these poles and powers have free action and proper stimulus in a suitable environment, they determine first the germ and afterwards the complete organism.