=Thrush.=--_Treatment._--Cut away the parts of the frog that seem to be destroyed; cleanse daily with castile soap, and apply muriatic acid, or a little tar mixed with salt on oakum or tow. =Colic.=--The mule is quite subject to this complaint. Too much cold water or changes of grain will produce it. The animal swells up, pants, looks around at his sides, paws, sweats above the eyes and on the flanks, becomes very restless, lying down and suddenly springing to his feet, lies down again, etc. _Treatment._--Drench with one ounce of chloral-hydrate in a half pint of water or two ounces of sulphuric ether and two ounces of tincture of opium in half pint of linseed oil, repeating the dose an hour afterwards if not relieved; or 2 oz. oil of turpentine, 1 oz. tinct. opium given in 12 oz. linseed oil or a pint of thick gruel. The belly should be well hand-rubbed and the animal walked about. Inject warm soap-suds. =Cramp.=--_Treatment._--A good hand-rubbing. =Mange.=--_Treatment._--Rub the animal with a mixture of hog's lard and sulphur, two pints of the latter to one pint of the former; cover with blanket; two days later wash clean with soft soap and water; blanket for a few days to avoid cold. Feed bran-mashes, plenty of salt and water. =Grease.=--This is a diseased state of the skin of the legs, and more especially the hind ones. In the early stages it consists of an inflammation of the sweat-glands, followed by an offensive oily discharge. The principal cause is uncleanliness, or by washing the legs with cold water and not properly drying them afterwards. _Treatment._--Without cleanliness medical remedies are worthless. Apply poultices; leave them on half a day. Boiled turnips, carrots, bread and milk, or bran and hot water are all good. Apply Gombault's balsam, one part to four parts of glycerine, once every two days in chronic cases. Or clean the parts well with castile soap and warm water, and use an ointment made of powdered charcoal two ounces, lard or tallow four ounces, sulphur two ounces, mix thoroughly and rub in well by hand. Or gunpowder and lard or tallow, equal parts, is good; or dress with carbolized oil or oxide of zinc ointment. =Glanders.=--A highly infectious and contagious disease of the lungs; incurable, and communicable to man.