Pathological data completely confirm this view. Ehrlich at least, in an
enormous number of cases, has never once succeeded in confirming the
existence of a purely splenic form from the blood examination[33].
The conditions in myelogenic leukaemia are quite similar, for foci of
myeloid tissue may appear in the spleen or lymph glands according to the
kind of metastasis. As it is the proliferation of the myeloid tissue and
not the accompanying swelling of spleen or lymph glands that is specific
in the process, the nomenclature "lienomedullary or medullary-lymphatic"
leukaemia must also be described as illogical and misleading.
We distinguish then, from the histological standpoint, but two forms of
leukaemia:
1. =leukaemic processes with proliferation of lymphoid tissue=:
"~lymphatic leukaemia~";
2. =leukaemic processes with proliferation of myeloid tissue=:
"~myelogenic leukaemia~."
The accompanying clinical phenomena may be indicated by simple
unequivocal amplifications, for instance, "lymphatic leukaemia with
enlargement of the spleen or of the liver"; "myelogenic leukaemia with
enlargement of the lymph glands," &c.
From our present knowledge, which, it may be remarked, is still far from
full, we may assume that lymphatic and myelogenous leukaemia have quite
a different aetiology. The recent discovery of Loewit should be decisive
on this point, for he demonstrated in myelogenic leukaemia the presence
of forms like plasmodia within the white blood corpuscles, but was
unable to find them in lymphatic leukaemia.
The necessity of separating lymphatic from myelogenic leukaemia is
further shewn by the fundamental clinical differences between them.
~Lymphatic leukaemia~ falls clinically into two readily distinguishable
forms. In the first place acute lymphatic leukaemia, characterised by its
rapid course, the small splenic tumour, the tendency to petechiae and to
the general haemorrhagic diathesis. By its startling course this disease
has given all observers the impression of an acute infectious process.
Public-domain text, read in full here on John Shaqi.
Reviews
Reviews
No reviews yet
Be the first to share your thoughts on this work.
Elsewhere in the archive
Join the Discussion
Join the discussion
Sign in to leave a comment or review.
Sign InorCreate an account