The memory of that cruel wrong long rankled in the mind of the Breretons, and the recollection may not improbably have had its influence on Sir William Brereton, who a century later did so much to accomplish the overthrow of monarchy, and who in this way may be said to have avenged the death of his kinsman, and thus have added one of those retributive parallels of which history furnishes so many instances. Sir William Brereton, who came to so untimely an end in 1536, had a younger brother, Urian Brereton, who in his earlier life was also one of the Grooms of the Privy Chamber. In 1526 he was appointed Ranger of Delamere Forest, and the same year Escheater of Cheshire, the latter an office he also held in the successive reigns of Edward VI., Mary, and Elizabeth, until his death in 1577. On the voluntary seclusion of Sir John Stanley, Urian Brereton married his divorced wife, Margaret, the daughter of William Honford, and thus became the founder of the line of Brereton of Handforth. The vindictive feeling which Henry manifested towards Sir William Brereton was not extended to the person of his younger brother, for the King, as if to mark the appeasement of his wrath, not only retained him in his position as Groom of the Privy Chamber, but also conferred other offices of distinction upon him. On the 8th July, 1538, he had a grant for life of the office of Attorney of the King in the counties of Chester and Flint; and on the 1st of August following he had a grant for life in survivorship of the office of Sheriff of the county of Flint on the surrender of the same by his kinsman, John Brereton, on whom it had been bestowed four months previously, and on the 16th of June, 1543, he and Randle Cholmondeley had conferred upon them the appointment for life, in survivorship, of the office of Attorney of the Earl of Chester (the young Prince Edward) in the counties of Chester and Flint. In 1544 he accompanied the Earl of Hertford in the expedition to Scotland to demand the infant Queen Mary, who had been promised in marriage to the King's son, Edward Earl of Chester, and he was present at the burning of Leith, where, in acknowledgment of his valorous deeds, he received the honour of knighthood. Shortly after the expedition to Scotland Sir Urian Brereton had the misfortune to lose his wife, Dame Margaret, who died at Handforth Hall, though the exact date of her decease has not been ascertained, the registers of Cheadle, where doubtless she was buried, not commencing until 1558. Her manors and lands descended to the son by her first husband, John Stanley, who on the 24th May, 1 Edward VI. (1547) entered into a covenant with Sir Urian Brereton under which the estates were settled between them.