On the 7th of July, 1550, Sir Urian and his relative, Richard Brereton, Esq., had conferred upon them for life, in survivorship, the office of Escheater of the county of Flint, and shortly after he commenced the rebuilding of the Hall of Handforth, completing it in 1562, as the inscription over the door, which has been already given, testifies. He also about the same time erected the handsome carved oak screen in the Brereton chantry at Cheadle church, placing upon it his initials, V. B., and his punning rebus, a briar and a tun. After the death of Dame Margaret Sir Urian again entered the marriage state, his second wife being Alice, the third daughter of Sir Edmund Trafford, of Trafford, Esq., and the widow of Sir William Leyland, of Morleys Hall, in Astley. His death occurred at Handforth Hall on the 19th of March, 1577, and twelve days later his remains were interred at Cheadle. By his first wife he had, as the inscription over the porch at Handforth records, six sons and two daughters, and by his second wife, who survived him little more than a year, one son and four daughters. His Inquisition was taken at Knutsford on the 28th March, 1580, when Randle Brereton, his eldest son, then of the age of forty, was found to be his heir; he did not, however, long enjoy possession, his death occurring on the 30th December, 1583, when, being unmarried, the estates, in accordance with a deed of settlement of 1575, devolved upon his younger brother, William Brereton, who five years previously, had been united in marriage with Katherine, daughter of Roger Hurleston, of Chester, and who was at the time described as "of the Nunneryes, Chester," a house and lands which the "Defender of the Faith" had taken from the fair nuns of Chester and given to his favourite, Sir Urian Brereton, the founder of the Handforth line. This William served the office of Sheriff of the county in 1590, and died at Handforth on the 5th June, 1601, at the age of fifty-three. He was buried at Cheadle, and Mr. Earwaker gives a copy of his funeral certificate transcribed from the Lansdowne MSS. in the British Museum (879 fo. 18):-- William Brereton of Honford Esquier died the fifth day of June A.D. 1601; he maryed Katherine daughter of Roger Hurlestonne of Chester, gent. and has issue three sonnes and two daughters, viz. Urian first sonne died young, Richard third sonne died young, Jane eldest daughter died young. William Brereton sonne and heire married Margaret daughter of Richard Holland of Denton in the county of Lancaster Esq. Dorothie Brereton only daughter now living.