The flank companies joined the armament under General Sir Charles (afterwards Earl) Grey, who effected a landing at three different points on the island of _Martinique_, in February, 1794, and accomplished in a short period the conquest of that valuable colony. The grenadier brigade under His Royal Highness Prince Edward, afterwards the Duke of Kent, and the light infantry under Major-General Dundas, were engaged in the conquest of _St. Lucia_ in the beginning of April. After the conquest of St. Lucia, an attack was made on _Guadaloupe_, and that valuable island was speedily rescued from the power of the republican government of France. The regiment proceeded to the island of Martinique, where it was joined by the flank companies. Two hundred men, commanded by Lieut.-Colonel Lysaght, proceeded to the island of _St. Domingo_, and formed part of the garrison of Cape St. Nicholas Mole: and five companies joined the garrison of _Busy-town_, which place was besieged by the enemy. In April, the TWENTY-SECOND, Twenty-third, and Forty-first regiments, with some other troops, embarked under the command of Brigadier-General John Whyte, for the attack of _Port-au-Prince_, the capital of the French possessions in the island of _St. Domingo_. A landing was effected on the 31st of May; some severe fighting occurred, in which the TWENTY-SECOND distinguished themselves: _Fort Bizzotton_ was captured, and the enemy was forced to abandon _Port-au-Prince_, which was taken possession of by the British troops. The regiment had Captain Wallace killed on this occasion, also several private soldiers killed and wounded. Unfortunately a malignant fever broke out in the town, and the British lost forty officers and six hundred soldiers by disease within two months after the capture of the place. A detachment of the regiment formed part of the garrison of _Fort Bizzotton_, which was attacked by two thousand of the enemy on the 5th of December. The British defended their post with great gallantry, and repulsed the assailants. Lieutenant Hamilton of the TWENTY-SECOND distinguished himself. Another portion of the regiment was stationed at Jeremie, and a detachment at Irois. [Sidenote: 1795] Having sustained severe loss from the climate of St. Domingo, the regiment was relieved from duty at that island, and returned to England in 1795. Lieut.-General Dundas was removed to the Seventh Light Dragoons, and the colonelcy of the TWENTY-SECOND was conferred on Major-General William Crosbie, from the Eighty-ninth regiment. [Sidenote: 1798] The regiment was stationed in England recruiting its ranks until December, 1798, when it proceeded to Guernsey. Major-General Crosbie died this year, and was succeeded by Major-General John Graves Simcoe, from the Eighty-first regiment. [Sidenote: 1799] In November, 1799, the regiment was withdrawn from Guernsey, and landed at Portsmouth on the 15th of that month.