The authors of the oldest herbals of the 16th century, Brunfels, Fuchs, Bock, Mattioli and others, regarded plants mainly as the vehicles of medicinal virtues; to them plants were the ingredients in compound medicines, and were therefore by preference termed ‘simplicia,’ simple constituents of medicaments. Their chief object was to discover the plants employed by the physicians of antiquity, the knowledge of which had been lost in later times. The corrupt texts of Theophrastus, Dioscorides, Pliny and Galen had been in many respects improved and illustrated by the critical labours of the Italian commentators of the 15th and of the early part of the 16th century; but there was one imperfection which no criticism could remove,—the highly unsatisfactory descriptions of the old authors or the entire absence of descriptions. It was moreover at first assumed that the plants described by the Greek physicians must grow wild in Germany also, and generally in the rest of Europe; each author identified a different native plant with some one mentioned by Dioscorides or Theophrastus or others, and thus there arose as early as the 16th century a confusion of nomenclature which it was scarcely possible to clear away. As compared with the efforts of the philological commentators, who knew little of plants from their own observation, a great advance was made by the first German composers of herbals, who went straight to nature, described the wild plants growing around them and had figures of them carefully executed in wood. Thus was made the first beginning of a really scientific examination of plants, though the aims pursued were not yet truly scientific, for no questions were proposed as to the nature of plants, their organisation or mutual relations; the only point of interest was the knowledge of individual forms and of their medicinal virtues.