Quesada's Administration—The Oidor Zorita Gathers the Natives into Towns—Expedition against the Lacandones—Its Failure—Landecho Appointed Quesada's Successor—His Residencia Taken by the Licentiate Brizeño—Famine, Pestilence, and Earthquake in Guatemala—The Audiencia of the Confines Removed to Panamá—And Again Transferred to Guatemala—Gonzalez Appointed President—He is Succeeded by Villalobos—Changes in Church Affairs—Death of Bishop Marroquin—Quarrels between the Dominicans and Franciscans—Bishops Villalpando and Córdoba—Fracas between two Ecclesiastics—Administration of President Valverde, Rueda, Sandé, and Castilla—Industrial Condition of the Province 358 CHAPTER XXII. AFFAIRS IN PANAMÁ. 1551-1600. Revolt of the Cimarrones—Pedro de Ursua Sent against Them—A Second Revolt—Bayano Caught and Sent to Spain—Regulations concerning Negroes—Commercial Decadence—Restrictions on Trade—Home Industries—Pearl Fisheries—Mining—Decay of Settlements—Proposed Change in the Port of Entry—Its Removal from Nombre de Dios to Portobello—Changes in the Seat of the Audiencia—Tierra Firme Made Subject to the Viceroy of Peru—Defalcations in the Royal Treasury—Preparations for Defence against Corsairs and Foreign Powers 386 CHAPTER XXIII. DRAKE AND OXENHAM'S EXPEDITIONS. 1572-1596. Drake's Attack on Nombre de Dios—Panic among the Inhabitants—Stores of Treasure—Retreat of the English—They Sail for Cartagena—And Thence for the Gulf of Urabá—Visit to the Isle of Pinos—The Ships Moved to the Cabezas Islands—Second Expedition to Cartagena—March to the Isthmus—Drake's First Glimpse of the South Sea—Ambuscade Posted near Cruces—The Bells of Approaching Treasure Trains—The Prize Missed through the Folly of a Drunken Soldier—Capture of Cruces—Thirty Tons of Gold and Silver Taken near Nombre de Dios—Voyage on a Raft—The Expedition Returns to England—Oxenham's Raid—Drake's Circumnavigation of the Globe—His Second Voyage to the West Indies—His Final Expedition—His Death and Burial off Portobello 404 CHAPTER XXIV. NICARAGUA AND COSTA RICA. 1551-1600.