enforce his will in spite of the protests that were raised. And so under the wise and conciliatory but firm administration of Margaret during a decade of almost continuous religious and international strife--a decade marked by such great events as the rapid growth of the Reformation in Germany, the defeat and capture of Francis I at Pavia, the sack of Rome by the troops of Bourbon and the victorious advance of the Turks in Hungary and along the eastern frontier of the empire--the Netherland provinces remained at peace, save for the restless intrigues of Charles of Egmont in Gelderland, and prospered. Their wealth furnished indeed no small portion of the funds which enabled Charles to face successfully so many adversaries and to humble the power of France. The last important act of Margaret, like her first, was connected with the town of Cambray. In this town, as the representative and plenipotentiary of her nephew the emperor, she met, July, 1529, Louise of Savoy, who had been granted similar powers by her son Francis I, to negotiate a treaty of peace. The two princesses proved worthy of the trust that had been placed in them, and a general treaty of peace, often spoken of as "the Ladies' Peace," was speedily drawn up and ratified. The conditions were highly advantageous to the interests of Spain and the Netherlands. On November 30 of the following year Margaret died, as the result of a slight accident to her foot which the medical science of the day did not know how to treat properly, in the 50th year of her age and the 24th of her regency. Charles, who had a few months previously reached the zenith of his power by being crowned with the iron crown of Lombardy and with the imperial crown at the hands of Pope Clement VII at Bologna (February 22 and 24, 1530), appointed as governess in Margaret's place his sister Mary, the widowed queen of Louis, King of Hungary, who had been slain by the Turks at the battle of Mohacs, August 29, 1526.