The revolutions and wars, caused by the invasion of Italy by the French and the Spaniards during the closing years of the fifteenth century and the early portion of the sixteenth, dealt a serious blow to Humanism in Florence, Milan, Venice, and other Italian centres. But the misfortunes of those cities served to strengthen the movement at Rome. Julius II. (1503-13) proved himself a generous patron of literature and in a special manner of art. Men like Giuliano da Sangello, Sansovino, Bramante, Michael Angelo, and Raphael were invited to Rome and induced to devote their genius to the service of religion and the glory of the Papacy. On the death of Julius II. in 1513 the complete triumph of the Humanist movement in Rome was assured by the election of Giovanni de' Medici who took the name of Leo X. (1513-21).[10] As the son of Lorenzo the Magnificent, to whom Florence owes its literary renown, and as the pupil of the celebrated Humanists, Poliziano and Marsilio Ficino, he was committed almost of necessity to the Humanist movement. Scholars and artists flocked to Rome from all sides to greet the new Pope and to assure themselves of his favour and protection. Under the new regime literary merit was the principal qualification sought for in candidates aspiring to the highest ecclesiastical honours. The Roman University was reorganised; the search for manuscripts was renewed with vigour; a new college for the promotion of Greek studies in Rome was founded, and the services of Lascaris and Musuro were secured; and artists like Raphael and Bramante received every encouragement. Humanism was at last triumphant in Rome, but, unfortunately, its triumph was secured at the expense of religion. Nor was Humanism destined to enjoy the fruits of the victory for a lengthened period. The outbreak of the Reformation and the capture of Rome by the soldiers of Charles V. turned the attention of the Popes to more pressing concerns.