In April 1867, the home of Dr. Morse's Indian Root Pills and of the other proprietary remedies was transferred from New York City to Morristown, a village of 300 inhabitants on the bank of the St. Lawrence River in northern New York State. This was not, however, the initial move into this area; three or four years earlier William H. Comstock had taken over an existing business in Brockville, Ontario, directly across the river. No specific information as to why the business was established here has been found, but the surrounding circumstances provide some very good presumptions. The bulk of the Comstocks' business was always carried on in rural areas--in "the back-woods." Specifically, the best sales territory consisted of the Middle West--what was then regarded as "The West"--of the United States and of Canada West, i.e., the present province of Ontario. A surviving ledger of all of the customers of Comstock & Brother in 1857 supplies a complete geographic distribution. Although New Jersey and Pennsylvania were fairly well represented, accounts in New York State were sparse, and those in New England negligible. And despite considerable travel by the partners or agents in the Maritime Provinces, no very substantial business was ever developed there. The real lively sales territory consisted of the six states of Ohio, Indiana, [Footnote 7: _National Cyclopedia of American Biography_, IV:500.] Illinois, Michigan, Wisconsin, and Iowa, which accounted for over two thirds of all domestic sales, while Canada West contributed over 90 percent of Canadian sales. More regular customers were to be found in Canada West--a relatively compact territory--than any other single state or province. The number of customers of Comstock & Brother in 1857 by states and provinces follows: Alabama 12 Arkansas 1 Connecticut 3 Delaware 5 D.C. 1 Florida 5 Georgia 15 Illinois 415 Indiana 298 Iowa 179 Kansas Ter. 1 Kentucky 21 Louisiana 7 Maine 2 Maryland 21 Massachusetts 5 Minnesota Ter. 6 Mississippi 8 Missouri 32 Michigan 194 New York State 88 New York City 3 New Jersey 212 New Hampshire 1 North Carolina 9 Ohio 179 Pennsylvania 192 Rhode Island 2 South Carolina 5 Tennessee 21 Texas 1 Virginia 30 Wisconsin 303 New Brunswick 15 Nova Scotia 19 Canada East (Quebec) 7 Canada West 434 Total United States 2,277 Total Canada 475