One of the most remarkable events in the history of this people is the invention of a Cherokee alphabet, by George Guess, a native Cherokee. In the account of the mission, this alphabet is said to furnish, probably, the most perfect orthography in the world. There has been a paper published in the Cherokee nation, partly in the English, and partly in the native language, and edited with considerable ability. Three presses are employed by the mission in printing books, principally for this tribe, though some are struck off in other languages. Since 1835, besides the Gospels of John and Matthew, and the Epistles of John, there have been printed, at one press, not less than thirty-two different works, nearly all of which were above twenty pages each, making an aggregate of upwards of 2,000,000 pages. The whole number of pages printed among the Cherokees since 1828, as appears by the last report of the American Board, is 4,725,000. Five schools, under the care of the mission, contain about one hundred and sixty Cherokee children. Some interesting cases of improvement have occurred among this nation, on which, were there space for it, it would be pleasing to dwell. The Cherokees bid fair, if no untoward events occur, to realize the most sanguine expectations of their friends. Much sympathy has been excited for them, at various periods, during the last thirty years, and especially when they were driven from their loved homes, and the territory guarantied to them by so many treaties; and words of burning eloquence were called forth from some of the most eloquent speakers in the halls of Congress, in depicting the injustice and cruelty with which they have been treated. It is to be hoped that the experiment they are now making may be permitted to go on to its completion, without any further invasions of their rights and happiness. Besides these principal tribes, who are deriving benefit from missionaries and schools among them, there are missionary stations among the Pawnees, the Sioux, Shawanese, Ottawas, Potawatomies, and other tribes. By treaty, large portions of land, or annual sums, have been set apart for the purposes of education, agriculture, and such other aids to their civilization as appear most desirable. The aversion to labor among some of these nations is said to be gradually wearing off, and idolatry and superstition are becoming eradicated. They still retain their ancient forms of government by chiefs.