Hence it was the duty of Englishmen to endeavor to comfort them, if possible give them satisfaction for their innocent blood shed in this kingdom, and enter into friendly intercourse with them. This work also defends the Jews against the accusation of having crucified Jesus. The death of Jesus took place at the instigation of the Synhedrion, not of the people. In most impressive terms it urges the English to comfort the afflicted and unhappy Jews. The pope and his adherents, he said, would be enraged at the kind treatment of the Jews, for they still inflicted cruelty and humiliation upon the people of God, the popes compelling the Jews to wear opprobrious badges, and Catholics avoiding all contact with them, because they abhorred idols and heathen worship. This work, which, more than friendly, absolutely glorified the Jews, excited the greatest attention in England and Holland. Manasseh ben Israel was delighted with it, thinking that he was near his object, especially as his friend Holmes at once communicated with him on the subject, saying that he himself was about to prepare a work on the millennium, in which he would emphasize the importance of the Jews in the molding of the future. Manasseh ben Israel immediately set to work to do his share towards the realization of his object. He, however, as well as the Christian mystics in England, had one anxiety; what had become of the lost Ten Tribes banished by the Assyrian king Shalmanassar? A restoration of the Jewish kingdom without these Ten Tribes seemed impossible, nay, their discovery was the guarantee of the truth of the prophetic promises. The union of Judah and Israel which some of the prophets had impressively announced would remain unfulfilled if the Ten Tribes had ceased to exist. Manasseh, therefore, laid great stress upon being able to prove their existence somewhere. Fortunately he was in a position to specify the situation of the Ten Tribes. Some years before, a Jewish traveler, named Montezinos, had affirmed on oath that he had seen native Jews of the tribe of Reuben, in South America, and had held communication with them. The circumstantiality of his tale excited curiosity, and inclined his contemporaries to belief. Antonio de Montezinos was a Marrano, whom business or love of travel had led to America. There he had stumbled upon a Mestizo (Indian), who had excited in him a suspicion that members of his race were living in America, persecuted and oppressed by the Indians, as the Indians had been by the Spaniards, and later experiences confirmed the suspicion.