The first encounter between our sturdy Anglo-Saxon forefathers and the red man of the forest occurred in 1666, two years after William Drummond took up the reins of government in Albemarle. After this trouble little is recorded, nor is Pasquotank nor any of her precincts mentioned in reference to the Indian War. But as the majority of the settlers in North Carolina then lived along the shores of Little River and the Pasquotank, we may feel sure that the men of this county were prominent in subduing their savage foes, who, as Captain Ashe records, "were so speedily conquered that the war left no mark upon the infant settlement." From then until the terrible days of the Tuscarora Massacre of 1711, the county, and Albemarle as a whole, rested from serious warfare; but these years can hardly be termed peaceful ones for the settlers in this region. The Culpeper Rebellion, the dissatisfaction caused by the tyrannical and illicit deeds of Seth Sothel, the disturbance caused by Captain Bibbs, who claimed the office of governor in defiance of Ludwell, whom the Lords had appointed to rule over Carolina, and the Cary troubles, all combined to keep the whole Albemarle district in a state of confusion and disorder for many years. But all of these quarrelings and brawlings were hushed and forgotten when in September, 1711, the awful tragedy of the Tuscarora Massacre occurred. Though the settlers south of Albemarle Sound, in the vicinity of Bath and New Bern, and on Roanoke Island, suffered most during those days of horror, yet from the letters of the Rev. Rainsford and of Colonel Pollock, written during these anxious days, we learn that the planters north of the sound came in for their share of the horrors of an Indian uprising that swept away a large proportion of the inhabitants of the colony, and left the southern counties almost depopulated. Though nearly paralyzed by the blow that had fallen upon the colony, which, in spite of difficulties, had been steadily growing and prospering, the officers of the government as soon as possible began to take steps to punish the Tuscaroras and their allies for the unspeakable atrocities committed by them during the awful days of the massacre, and also to devise means for conquering the savage foes who were still pursuing their bloody work. All the able-bodied men in the State were called upon to take part in the warfare against the Indians. But so few were left alive to carry on the struggle, that Governor Hyde was compelled to call upon the Governor of South Carolina and of Virginia to come to his aid in saving the colony from utter extinction. South Carolina responded nobly and generously. Virginia, for various reasons, sent but little aid to her afflicted sister colony. For two long years the war continued, until at last the Indians were conquered, the surviving hostile Tuscaroras left the State, and peace was restored to the impoverished and sorely tried colony.