If persons affected by severe carbonic oxide poisoning are withdrawn from the poisonous atmosphere after having reached the stage of unconsciousness, they may recover, but often with difficulty; not infrequently—in spite of suitable treatment—death occurs some considerable time later from the symptoms described above. Still, in many cases, under the influence of right treatment, gradual recovery has been brought about, even after long unconsciousness accompanied by repeated convulsions. In the rescued the symptoms described as characteristic of the first stage often continue for at least a day. Further, they are liable to a number of serious after effects, such as severe inflammation of the lungs due to infection by the entrance of vomited matter into the air passages, skin affections (rashes), and especially severe nervous and mental affections. Frequently these develop from centres of softening in the brain or from inflammation of the peripheral nerves (neuritis); occasionally the poisoning may really only be the predisposing cause for the outbreak of an existing psychical disease. It is not our task to enumerate all the extremely varied disturbances which are observed after carbonic acid gas poisoning. Neuralgias and paralyses have been described as associated with the peripheral nerve symptoms over areas supplied by different nerves; various forms of diseases of the brain and spinal cord (poliomyelitis, paralysis, sclerosis, &c.); and finally a series of psychoses (neurasthenia, melancholia, mania, &c.), occasionally passing into dementia and imbecility. Glycosuria (sugar in the urine) has also been noted as a sequela. Chronic carbonic oxide poisoning, arising from continued inhalation of small quantities of the gas, sets in usually with symptoms similar to those of acute carbonic oxide poisoning; if the worker continues exposed to danger, severe symptoms may arise which point to marked alteration of the blood and later also of the digestion and bodily functions. Under certain circumstances severe nervous and mental affections are said to occur similar to those which we have mentioned as sequelæ of acute carbonic oxide poisoning (convulsions, disturbances of mental activity, symptoms which resemble progressive muscular atrophy, &c.). In acute carbonic oxide poisoning oxygen inhalation indefatigably continued and supported by artificial respiration is often successful. The serious danger from this form of poisoning renders it very necessary that in all premises where there is risk provision should be made for the administration of oxygen. The sequelæ can of course only be treated symptomatically. OXYCHLORIDE OF CARBON (PHOSGENE)