Influenza : $b An epidemiologic studyVaughan, Warren T. (Warren Taylor)
History
Influenza : $b An epidemiologic study
Vaughan, Warren T. (Warren Taylor)
Influenza
Having concluded that tuberculosis does protect in some measure against
influenza, Debré and Jacquet next discuss whether the latter has
increased the severity of tuberculosis in the subjects who were already
tuberculous. They review the literature and make their conclusions, not
from statistical records, but from general observations. They consider
first those cases of phthisis which are open cases when attacked, and
second, latent tuberculosis. Their conclusion concerning the first group
is that influenza does not have any effect on the rapidity of evolution
of the tuberculous process, except in very rare instances, such as an
occasional case of miliary tuberculosis following grip. As regards
latent tuberculosis, however, they do believe that the intercurrent
acute infection does cause in many cases a lighting up of a previously
entirely dormant tuberculosis. It seems rather difficult to reconcile
the two ideas. If one type of tuberculous individual is rendered more
susceptible to the ravages of consumption, it would seem reasonable to
expect that all types would be so affected.
The greatest difficulty in reaching a conclusion regarding the effects
of influenza on tuberculosis, and vice versa, is due to the fact that
the individuals studied are in all stages of the disease, and that each
individual reacts differently and in his own way. Opinions have been
based chiefly on clinical observations, and not on statistical study of
large series of cases, while from the nature of the conditions, even
statistical studies would not be without great fallacy.
Armstrong, found in a survey made in Framingham, Massachusetts, that 16
per cent. of the entire population was affected with influenza, but only
4 per cent. of the tuberculous group in the community. Most of these
latter were of the arrested type and were going about taking their part
in industry and exposed to the same degree of contact as was the case
with the normal population. The fatality rate was equally in contrast.
Armstrong concluded that there appeared to be a relative degree of
protection for the highly tubercularized. If we accept these figures at
their face value we must conclude then either that tuberculosis offers
some degree of protection against acute influenzal infection, or, that
the tuberculous of Framingham have been so well trained in sanitation
and personal hygiene, as a result of the Framingham demonstration, that
they have been able to protect themselves against the grip. In the
latter case we must look upon the result as a successful demonstration
of the principles of preventive medicine. Certainly this did play a
part, to the extent at least that individuals knowing themselves to be
infected with tuberculosis, and knowing themselves to be in the presence
of a pandemic, became more wary of crowd contact, and in case they did
become ill, they undoubtedly went to bed at the earliest opportunity.
Public-domain text, read in full here on John Shaqi.
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