Irritability : $b a physiological analysis of the general effect of stimuli in living substanceVerworn, Max
Science
Irritability : $b a physiological analysis of the general effect of stimuli in living substance
Verworn, Max
Irritability
A _summation of two excitations_ was observed already by _Exner_. This
investigator connected the abductor pollicis of the rabbit with an
apparatus for making graphic records. He then stimulated first the paw
and then the motor areas of the cerebral cortex with faradic shocks,
the intensity of which was just sufficient to bring about perceptible
effect. If both stimuli were simultaneously operative, an increase in
the response was observed. Even when the stimuli were sub-threshold
in type, as a result of summation there was a perceptible muscle
contraction. (Figure 56.) _Exner_ had at that time referred to this
increase of the response as “Bahnung” (reinforcement). However, the
word “Bahnung” has more than one meaning, for processes of various
types are involved in this term. Thus writers have differentiated real
and apparent “Bahnungen.” On account of this lack of clearness in the
meaning of the term “Bahnung,” I wish to discard its use as it is not
at all essential. We will speak simply of a _summation of excitation_,
for here it is simply a question of summation of two excitations of the
motor cells of the spinal cord.
[Illustration: Fig. 56.
Summation of two excitations in the rabbit. The one proceeds from the
paw, the other from the motor sphere of the cerebral cortex. _S_--Time
in seconds. _Pf_--Stimulation of the paw. _H_--Stimulation of the motor
sphere. _M_--Contractions of the abductor pollicis. (After _Exner_.) ]
_Fröhlich_ has shown that summation of two excitations upon a motor
cell of the anterior horn coming by way of different paths is more
readily obtained when the stimuli are somewhat strong, or when the
duration of the excitation processes in the ganglion cells are somewhat
prolonged by fatigue.
[Illustration: A B
Fig. 57.
Summation of two excitations in the spinal cord produced by stimulation
of the ninth and tenth posterior root. Lower line indicates faradic
stimulation of the tenth, upper line of the ninth root. ]
[Illustration: A B
Fig. 58.]
[Illustration: Fig. 59.]
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