Irritability : $b a physiological analysis of the general effect of stimuli in living substanceVerworn, Max
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Irritability : $b a physiological analysis of the general effect of stimuli in living substance
Verworn, Max
Irritability
The greatest number of instances of the interference of two series
of stimuli have been given to us by investigation of the physiology
of the nervous system. In the functionation of the nervous system
the fact that two series of stimuli from different tracks affect
the same ganglia plays a very important rôle. It is this to which
_Sherrington_[191] has alluded as “_the principle of the common path_.”
Where two nervous excitations involve the same paths, there arises
an interference of the effect of the two series of stimuli, for the
impulses in the nervous system, as already stated, possess a rhythmic
character. This principle has a broad application in the phenomena of
association in the cerebral cortex. The simpler and, therefore, the
most easily understood cases are, however, in the spinal cord. The
motor neurons of the anterior horns of the spinal cord are the junction
of a great number of tracks, for example, the sensory neurons of the
spinal cord at different levels, the neurons of the cerebellum, the
pyramidal tracks from the motor areas of the cerebral cortex, etc.
On the contrary, for example, the sensory neurons of the spinal cord
are strictly “_private_ paths” in the sense of _Sherrington_, for
excitation can enter by this means only from the special paths of the
spinal ganglia and, therefore, from the periphery. The motor neurons
of the anterior horns offer, therefore, excellent opportunities for
the experimental investigation of the interference of two series
of excitations which enter by different paths. The spinal cord
consequently has become a much-used object of investigation for this
purpose. In fact, we can observe and produce all types of interference
in the spinal cord. These conditions have been quite thoroughly
investigated by _Sherrington_[192] and his coworkers on the dog, and
_Fröhlich_,[193] _Vészi_,[194] _Tiedemann_[195] and _Satake_[196] on
the frog.
[191] _Sherrington_: “Ueber das Zusammenwirken der Rückenmarksreflexe
and das Princip der gemeinsamen Strecke.” Ergebnisse der Physiologie.
Jahr. IV, 1905.
[192] _Sherrington_: “The integrative action of the nervous system.”
New York 1906.
[193] _Fr. W. Fröhlich_: “Der Mechanismus der nervösen
Hemmungsvorgänge.” Med. Natur. Arch. Bd. I, 1907. The same: “Beiträge
zur Analyse der Reflexfunction des Rückenmarks, etc.” Zeitschr.
f. allgem. Physiologie Bd. IX, 1909. The same: “Das Princip der
scheinbaren Erregbarkeitssteigerung.” _Ibid._
[194] _Julius Vészi_: “Der einfachste Reflexbogen im Rückenmark.”
Zeitschr. für allgem. Physiol. Bd. IX, 1910.
[195] _Tiedemann_: “Untersuchungen über das absolute Refractärstadium
und die Hemmungsvorgänge im Rückenmark des Strychninfrosches.”
Zeitschr. f. allgem. Physiologie Bd. X, 1910.
[196] _Satake_: The researches are not yet published.
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