In order to test the truth of this hypothesis, I made the following
experiments. Having first noted the rate of the rhythm under faradaic
stimulation of minimal intensity, without shifting the electrodes
or altering the intensity of the current, I discarded the faradaic
stimulation, and substituted for it single induction shocks thrown
in with a key. I found, as I had hoped, that the _maximum_ number
of these single shocks which I could thus throw in in a given time
_so as to procure a response to every shock_, corresponded with the
number of contractions which the tissue had previously given during
a similar interval of time when under the influence of the faradaic
current of similar intensity. To make this quite clear, I shall
describe the whole course of one such experiment. The deganglionated
tissue under the influence of minimal faradaic stimulation manifested
a perfectly regular rhythm of thirty contractions per minute, or one
contraction in every two seconds. While the position of the platinum
electrodes and the intensity of the current remained unchanged,
single induction shocks were now administered with a key at any
intervals which might be desired. It was found that if these single
induction stimuli were administered at regular intervals of two
seconds or more, the tissue responded to every stimulus; while if
the stimuli were thrown in more rapidly than this, the tissue did
not respond to every stimulus, but only to those that were separated
from one another by an interval of at least two seconds' duration.
Thus, for instance, if the shocks were thrown in at the rate of one
a second, the tissue only, but always, responded to every alternate
shock. And similarly, as just stated, if any number of shocks were
thrown in, the tissue only responded once in every two seconds. Now,
as this rate of response precisely coincided with the rate of rhythm
previously shown by the same tissue under the influence of faradaic
stimulation of the same intensity, the experiment tended to verify
the hypothesis which it was designed to test.
[Illustration: Fig. 27.]
Public-domain text, read in full here on John Shaqi.
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