6. _Digitalin._--The first effect of this poison on Sarsia is to
quicken the swimming motions, and then to enfeeble them progressively
till they degenerate into mere spasmodic twitches. The manubrium and
tentacles are now strongly retracted, while the nectocalyx is drawn
together so as to assume an elongated form. The latter is now no
longer responsive either to tentacular or to direct stimulation; but
the tentacles and manubrium both remain responsive to stimuli applied
either directly to themselves or to the neuro-muscular tissue of the
bell. Death always takes place in very strong systole; and as this is
an exceedingly unusual thing in the case of Sarsia, there can be no
doubt that, in this respect, the action of the digitalin is different
on the Medusæ from what it is on the heart.
On the various species of Tiaropsis, digitalin at first causes
acceleration of the swimming movements, with great irregularity and
want of co-ordination. Next, strong and persistent spasms supervene,
which give the outline of the nectocalyx an irregular form; and every
now and then this unnatural spasm gives place to convulsive swimming
motions. Evidently, however, the spasm becomes quite persistent and
excessively strong. The manubrium of Tiaropsis indicans crouches to
its utmost, and the animal dies in strong systole.
7. _Atropin._--In the case of Sarsia atropin causes convulsive
swimming motions. The systoles next become feeble, and finally cease.
The nectocalyx is now somewhat drawn together in persistent systole,
with the manubrium and tentacles strongly retracted. Muscular
irritability remains after tentacular irritability has disappeared,
but it is then decidedly enfeebled.
In the various species of Tiaropsis the convulsions are strongly
pronounced. They begin as mere accelerations of the natural swimming
motions, but soon grow into well-marked convulsions, consisting of
furious bouts of irregular systoles following one another with the
utmost rapidity, and wholly without co-ordination. Occasionally
these movements are interrupted by a violent spasm, on which strong
shuddering contractions are superimposed.
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