5. _Veratrium._--In Sarsia the first effect of this poison is to
increase the number and potency of the contractions; but its later
effect is just the converse, there being then prolonged periods of
quiescence, broken only by very short swimming bouts consisting of
feeble contractions. The feebleness of the contractions gradually
becomes more and more remarkable, until at last it is with great
difficulty that they can be perceived at all; indeed, the progressive
fading away of the contractions into absolute quiescence is so
gradual that it is impossible to tell exactly when they cease. During
the quiescent stage the animal is for the first time insensible both
to tentacular and to direct stimulation of the contractile tissues.
That the gradual dying out of the strength of the contractions is
not altogether due to the progressive advance of central paralysis,
would seem to be indicated by the fact that contractions in
response to direct stimulation of the contractile tissues are no
more powerful, at any given stage of the poisoning, than are either
responses to tentacular stimulation or the spontaneous contractions.
Still, as we shall immediately see, in the various species of
Tiaropsis, irritability persists after cessation of the spontaneous
contractions. In Sarsia the nervous connections between the tentacles
and manubrium, and also between the tentacles themselves, are not
impaired during the time that the bell is motionless; and even
when the irritability of the bell has quite disappeared as regards
any kind of stimulation, the manubrium and tentacles will continue
responsive to stimuli applied either directly to themselves or to any
part of the neuro-muscular sheet of the bell.
The convulsions due to the action of veratrium are well marked in
the various species of the genus Tiaropsis. They consist of violent
fluttering motions without any co-ordination; but there are no
spasms, as in the case of strychnia poisoning. After the convulsions
have lasted for some time, a quiescent stage comes on, during which
the animal remains responsive to stimulation, though not abnormally
so. Recovery in unpoisoned water is rapid, the movements being at
first marked by an absence of co-ordination.
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