The selection of the spices depends entirely upon the flavor desired. Cinnamon, cassia, cloves, allspice, mace, pepper, paprika, cayenne pepper, mustard, ginger, coriander, bay leaves, caraway and celery seed, are all to be found in the various formulae. Some manufacturers spice lightly in order to retain the maximum of the base flavor, while others go to the opposite extreme on the misguided assumption that they will act as preservatives. The quantity used should be determined by the flavor desired and upon no other consideration. The spices may be used whole, ground, or in some cases as acetic acid or oil extracts. The whole spices are preferred by nearly all the manufacturers of high grade goods. They are more expensive, but give a different flavor from the extracts. The spices are weighed for each batch and are tied in a bag or placed in a wire basket and suspended in the kettle while cooking. Some use very large quantities and cook from only ten to twelve minutes in order to get a distinctive flavor. This is very expensive, as only a small quantity of the flavoring matter is extracted in such a short time. One of the serious objections to the use of the whole spices is that they may darken the ketchup and also cause some discoloration in the neck of the bottle. For that reason, black pepper and allspice in particular are being discarded, and oil of cloves is being used in part for the whole berries. The grade of the spice will also have an effect, the cheap stock being unsuitable for a bright clean product. Small quantities of ground cayenne pepper are used as a substitute for the black pepper. Acetic acid extracts of some of the spices are being used to a certain extent, but they have a peculiar harsh flavor that makes them undesirable. The oil extracts can be used to only a very limited extent, as they impart a flavor suggestive of the drug store. One method of making a nearly complete extraction of the spices is to place them in their proper proportion in vinegar a few weeks before the ketchup season begins and then add the spiced vinegar in the proper proportion to each batch. The result is different from that obtained by cooking, and the method is not recommended for first grade goods. The waste of spices in the usual process of manufacture is indicated by some work done by Mr. H. E. Bishop of the laboratory of the Indiana State Board of Health. He found that in making ketchup, when the boiling was kept up for thirty minutes, that only 27.8 per cent of the oil of cassia, 11.5 of the oil of cloves, and 33.3 per cent of the oil of allspice were extracted. (Unpublished report.)