Between July, 1905, and 1908, sixty-two cases of plumbism in children were admitted to the children’s hospital, and of these sixty-two cases thirteen had well-marked ocular symptoms. The paralysis of the muscles of the eye was almost invariably one of the external rectus, but other muscles were at the same time affected; occasionally paralysis of the whole of the oculo-motor muscles was seen with the exception of the superior oblique. It is worthy of note that amongst these children a very large number suffered, in addition to their eye paralysis, with foot-drop and wrist-drop, and, on the whole, suffered from foot-drop to a much larger extent than from paralysis of the hands. Galezowski[15] describes paralysis of accommodation of the eye, and in cases described by Folker[16] some amount of orbital paralysis was also present. 7. _Generalized Paralysis._--These types do not differ in form from the previously described types, except, perhaps, as regards their rapidity of onset. Where the onset is slow (chronic) the subject is usually one who has been previously affected with paralysis of the extensors of the hand, followed by development of the paralysis in the shoulders, hand, leg, thorax. In the acute form, paralysis may affect all the muscles in a given limb or group, and reduce them in a few days to a complete condition of paralysis. In extreme cases the patient lies on the back and is incapable of rising, and sometimes even unable to eat. The intercostals, diaphragm, and larynx, are also affected, while there is generally dyspnœa and aphonia. The muscles of the head and neck appear to escape. In these acute cases, pyrexia may be a common symptom. =Electrical Reactions.=--The diagnosis of the affected muscle is greatly assisted by careful examination of all the muscles in the affected physiological group by means of the galvanic and faradic currents. The battery for the purpose of testing the electrical reactions must have an available electromotive force of over 40 volts. A battery of thirty-two Leclanché dry cells is ample. For the faradic current, a small induction coil operated by two Leclanché cells is sufficient. One large, flat electrode should be used, and several smaller ones. The faradic current should be used first, as it stimulates the nerves directly, and the muscles only indirectly, through their nerve-supply. Each nerve trunk should be examined systematically. The motor points correspond for the most part with the points of entry of the motor nerves into the muscles which they supply. A small electrode, either a button or a small disc about the size of a sixpence, should be used for the examining electrode, while the larger electrode should be placed either on the abdomen or between the shoulders. The electrodes should be well soaked in normal saline.