When the lateral secretion theory is applied to the disseminated deposits of southeastern Missouri, we are confronted by enormous bodies of ore, absence of barite, non-crystallized condition of the galena except in local, small, evidently secondary deposits, and well-defined courses for the main and cross-runs of ore. The Bonne Terre orebody, which has been worked longest and most energetically, has attained a length of nearly 9000 ft., with a production of about 350,000 tons or $30,000,000 of lead, and is far from being exhausted. Orebodies recently opened are quite as promising. The country rock is not as broken nor as open as in central Missouri, and is therefore much less favorable for the lateral circulation of mineral waters, yet the orebodies vastly exceed those of the central region. Further, the Bonne Terre formation is heavily intercalated with thick sheets of shale that would hinder overlying waters from reaching the base of the ore-horizon, where most of the ore occurs, so that the leachable area would be confined to a very limited vertical range, or to but little greater thickness than the 100 ft. or so in which most of the orebodies occur. While I have always felt that such large bodies, showing relatively rapid precipitation of the lead, could not be satisfactorily explained except as having a deep-seated origin, the fact that the disseminated ore is practically non-argentiferous, or at least carries only one to three ounces per ton, has been a formidable obstacle. For the lead in the small fissure-veins that occasionally occur in the adjacent granite has always been reported as argentiferous. Thus the Einstein silver mine, near Fredericktown, worked a fissure-vein from 1 to 6 ft. wide in the granite. It had a typical complex vein-filling and structure, and carried galena that assayed from 40 to 200 oz. per ton. While the quantity of ore obtained did not justify the expensive plant erected to operate it, the galena was rich in silver, whereas in the disseminated ores at the Mine la Motte mine, ten miles distant, only the customary 1.5 oz. per ton occurs. Occasionally fine-grained specimens of galena that I have found in the disseminated belt would unquestionably be rated as argentiferous by a Western miner, but the assay showed that the structure in this case was due to other causes, as only about two ounces were found. An apparent exception was reported at the Peach Orchard diggings, in Washington county, in the higher or Potosi member of the third magnesian limestone, where Arthur Thacher found sulphide and carbonate ore carrying 8 to 10 oz. of silver per ton; and a short-lived hamlet, known as Silver City, sprang up to work them. I found, however, that these deposits are associated with little vertical fissure-veins or seams that unquestionably come up from the underlying porphyry.