I have had occasion to work out the nature of fossil remains, of which there was nothing left except casts of the bones, the solid material of the skeleton having been dissolved out by percolating water. It was a chance, in this case, that the sandstone happened to be of such a constitution as to set, and to allow the bones to be afterward dissolved out, leaving cavities of the exact shape of the bones. Had that constitution been other than what it was, the bones would have been dissolved, the layers of sandstone would have fallen together into one mass, and not the slightest indication that the animal had existed would have been discoverable. I know of no more striking evidence than these facts afford, of the caution which should be used in drawing the conclusion, from the absence of organic remains in a deposit, that animals or plants did not exist at the time it was formed. I believe that, with a right understanding of the doctrine of evolution on the one hand, and a just estimation of the importance of the imperfection of the geological record on the other, all difficulty is removed from the kind of evidence to which I have adverted; and that we are justified in believing that all such cases are examples of what I have designated negative or indifferent evidence--that is to say, they in no way directly advance the hypothesis of evolution, but they are not to be regarded as obstacles in the way of our belief in that doctrine. I now pass on to the consideration of those cases which, for reasons which I will point out to you by and by, are not to be regarded as demonstrative of the truth of evolution, but which are such as must exist if evolution be true, and which therefore are, upon the whole, evidence in favour of the doctrine. If the doctrine of evolution be true, it follows, that, however diverse the different groups of animals and of plants may be, they must all, at one time or other, have been connected by gradational forms; so that, from the highest animals, whatever they may be, down to the lowest speck of protoplasmic matter in which life can be manifested, a series of gradations, leading from one end of the series to the other, either exists or has existed. Undoubtedly that is a necessary postulate of the doctrine of evolution. But when we look upon living Nature as it is, we find a totally different state of things. We find that animals and plants fall into groups, the different members of which are pretty closely allied together, but which are separated by definite, larger or smaller, breaks, from other groups. In other words, no intermediate forms which bridge over these gaps or intervals are, at present, to be met with.