physiologists thought would be its effect, and then judging for myself. I certainly could not sign the paper sent me by Miss Cobbe, with its monstrous (as it seems to me) attack on Virchow for experimenting on the Trichinae. I am tired and so no more. Yours affectionately, CHARLES DARWIN. CHARLES DARWIN TO J.D. HOOKER. Down, April 14 [1875]. My dear Hooker, I worked all the time in London on the vivisection question; and we now think it advisable to go further than a mere petition. Litchfield (Mr. R.B. Litchfield, his son-in-law.) drew up a sketch of a Bill, the essential features of which have been approved by Sanderson, Simon and Huxley, and from conversation, will, I believe, be approved by Paget, and almost certainly, I think, by Michael Foster. Sanderson, Simon and Paget wish me to see Lord Derby, and endeavour to gain his advocacy with the Home Secretary. Now, if this is carried into effect, it will be of great importance to me to be able to say that the Bill in its essential features has the approval of some half-dozen eminent scientific men. I have therefore asked Litchfield to enclose a copy to you in its first rough form; and if it is not essentially modified may I say that it meets with your approval as President of the Royal Society? The object is to protect animals, and at the same time not to injure Physiology, and Huxley and Sanderson's approval almost suffices on this head. Pray let me have a line from you soon. Yours affectionately, CHARLES DARWIN. [The Physiological Society, which was founded in 1876, was in some measure the outcome of the anti-vivisection movement, since it was this agitation which impressed on Physiologists the need of a centre for those engaged in this particular branch of science. With respect to the Society, my father wrote to Mr. Romanes (May 29, 1876):-- "I was very much gratified by the wholly unexpected honour of being elected one of the Honorary Members. This mark of sympathy has pleased me to a very high degree." The following letter appeared in the "Times", April 18th, 1881:] CHARLES DARWIN TO FRITHIOF HOLMGREN. (Professor of Physiology at Upsala.) Down, April 14, 1881. Dear Sir,