And now at last remains to be spoken what word of cheer and hope our new outlooks may have given us for those who are already under the shadow of this sorrowful affliction. The dreams and aspirations and strenuous labours of the students of this disease have looked steadily toward the discovery of some definite and positive means of cure, but as yet full success lingers beyond their grasp. The methods for the early detection of tuberculosis which science has pointed out make it possible for affected persons to plan such modes of life and early seek such salubrious climates as promise a hope of recovery. We have studied closely the ways in which the cells of the body often successfully resist the incursions of the already seated germs, and learned how in many ways the natural forces of cure may be sustained and strengthened. We have learned much about certain complicating occurrences which often form the most serious features in the progress of tuberculosis of the lungs, and how they may be best avoided. And so to-day the outlook for those in the earlier stages of this disease is in a considerable proportion of cases extremely encouraging. It is no longer for us the hopeless malady which it was earlier believed to be. It is not necessarily a bitter losing fight upon which one enters who becomes aware that the finger of this disease is upon him. A long and happy and useful life may still be his if the conditions which favour his cure be early and intelligently fixed upon, and patiently and faithfully persisted in. The wise physician is here the best adviser in climate and regimen, as well as in the proper selection of remedial measures, and the earlier his counsel is sought and acted on, the brighter will usually be the outlook for recovery. Research in tuberculosis and the ministration of the physician should, and generally do, go hand in hand, and no time should be lost in bringing to the aid of the stricken what light and promise the studies of the laboratory day by day may yield. The great and beneficent work which has been accomplished by Trudeau in the Adirondack woods, in at once widening the bounds of knowledge of tuberculosis and in carrying to a successful issue in so many the varied and delicate processes of cure, is a cheering example of what may be accomplished with persistent devotion, by the light of our new knowledge, in mastering a malady so long considered hopeless. MALARIA AND MOSQUITOES GEORGE M. STERNBERG, M.D., LL.D.