LASTLY, Nothing is more known in Nature, than that Blood, by what Means soever extravasated, if it cannot get back again into the Vessels, will, after some Stagnation, run for the most Part into Grume; so that when a Fluctuation requires opening, little else than a coagulated Blood flows out: And if any one please to receive the Blood from an opened Vein into a warm Porringer, and afterwards place it in a luted Vessel upon a Sand Heat, as near as possible equal to that which is natural, he will find all Labour lost in endeavouring to produce thereby any Appearances of _Pus_ in it, either from its Colour, Smell, or any other of its requisite Properties. WHY then may we not conclude with some others of great Note, that _Pus_ is generated immediately from the nutritious Juice, not in the Arteries and Veins, but in other Vessels; in which Juice all the requisite Properties are to be found, as a Disposition to grow thick, without Smell, white, light, and of a smooth Consistence; and I take it to be very probable, that the _Pus_ is made from hence by the Assistance of the natural Heat, and the Conveyance of it by the forementioned Vessels into the Glands whereinto they are complicated, and not by any Means from the Venal Blood, and much less from the Arterial. BUT least I should seem to digress too far; the _Sanies_ thrown out by a Buboe is very different, sometimes thin and ichorous, at others thicker and more laudable, as in Abscesses that are not malignant; in Respect of its Smell, it is sometimes so extreamly fetid, as not to be endured by the Nose; but always the more plentifully it discharges, the better does the Patient fare afterwards: Nature finds a Vent this open Way to disengage her self from a pernicious Enemy. THE Number of Buboes was uncertain, sometimes one only appeared, at others, which was most commonly, two broke out at once; nay, there were met with Instances wherein all the Glands capable of it were tumified. Many Buboes at a Time infallibly demonstrated the Aggravation, and Dispersion of the virulent Taint; and on the contrary, but few shewed the Poison to be not so prevalent, more contracted, and brought to a narrower Compass for Expulsion. The Places, and Manner of their Eruption was very uncertain, sometimes one would appear in the right _Axilla_, and another on the contrary Side of the Groin; these Tumours would likewise sometimes last but a Day, and again insensibly vanish, that is, always when profuse Sweat arose; but whensoever they were drawn in again by any Mismanagement or Casualty, they would appear and vanish again many Times, and be very difficult afterwards to be fixed; and sometimes when they could be brought to Suppuration, and a plentiful Discharge, they would renew again, as we shall hereafter have further Occasion to observe.