_BLISTER-Plasters_ were applied to several Parts; as the Nape of the Neck, within-side the Arms, the Thighs, and Legs; and by these the Vessels were warmed, the Juices rendered more fluid, a _Stimulus_ given to the Sluggishness of Nature, and Passage made sufficiently large, for the Evacuation not only of superfluous Serosities and noxious Humours, but also for the pestilential Poison, which by this Artifice seemed to be turned out this Way; not to say any Thing of the Revulsion made hereby of Venom from the nobler Parts. FOR this Purpose, I once ordered a _Blister-Plaster_ to be applied within-side the Thigh, a little below a Buboe in the Groin, but by the Carelesness of the Nurse, it was laid upon the Buboe it self; which happening to prove fortunate, after obtained in Practice, in Expectation thereby to prevent the morbifick Humour from going back again, and to forward its Suppuration; but altho’ this was of Advantage in some Cases, it was yet much suspected by the more cautious Physicians and Surgeons, as for the most Part it brought too great an Inflammation all round it, and promoted a Strangury, which, by Excess of Uneasiness, greatly wasted the Spirits, and sunk the Patient’s Strength. THAT these Applications may certainly answer their End, the most sharp ought to be used: The following Composition never failed me in all my Practice; but before its Application, the Part was always rubbed with Vinegar. ℞ _Picis navalis +℥ v.+ galbani colat. +℥ j.+ ceræ +℥ j. [ss.]+ quibus simul liquatis, & ab igne semotis, adde pulv. cantharidum præp. +ʒ vij.+ vel +℥ j.+ fermenti veteris, sem. ameos ana +ʒ iij.+ euphorbii +ʒ j.+ cum aceti scillit. q. s. incorporentur, assiduè agitando, quoùsque cogantur in Emplastri massam._ THE Parts thus vesicated were never suffered to heal, till the Malignity of the Disease was spent; and to prevent their suddain drying up, they were continually stimulated by _Melilot_ Plasters sprinkled over with some Powder of _Cantharides_; which kept up a constant Drein of noxious Humours; but to asswage the great Heat and Inflammations, sometimes occasioned hereby, _Cole-wort_ Leaves were applied to them. YET although _Epispasticks_ did so much Service to the Infected, and sufficiently made amends for the Trouble and Pain they gave; yet they were not indifferently suitable to all Persons; As for Instance, where there was an Heat of Urin, or a continual Inclination to piss, where the _Sphincter_ of the Bladder was inflamed, or ulcerated, in an Hemorrhage, or to Women with Child, or having the _Menses_; and lastly, where there was a great _Languor_ upon the Spirits; it is also diligently to be considered when _Epispasticks_ are applied to Buboes or Carbuncles near upon Suppuration, that they do not fuse the Humours too much, to admit them going into a laudible _Pus_, and give such a _Stimulus_ to the Parts, as may sink the Spirits, and frustrate other Endeavours of Nature to help her self.