The objections that have been made against this practice, are founded rather in an aversion to novelty, however useful, than in an adherence to reason and experience. The strange imputation that a well established method of preserving many lives, is an attempt upon the prerogative of the Almighty, will make no impression upon any, who consider that the same thing may be urged against exhibiting medicines at all, either sanative or preventive, and the extraordinary methods that are often necessary to be made use of, to stop the progress of any particular disease. The benefits of inoculation appear every year, by fresh trials, greater and more certain. This dreadful, this destructive distemper is thereby rendered mild and manageable, and becomes rather a purgation of the body from the latent seeds of an expected disease, than creating a disease itself. It delivers people from those apprehensions, with which, till they have had the small-pox, they are always haunted. It frees them from the objections, that are continually made to their being received into any family, while they remain exposed to that disease in the natural way. It gives them courage to enter into the service of their country, either by land or sea; and protects them, while in that service, from the risque of being carried off, for want of those accommodations, which camps and ships rarely supply. To all these, if we add the general and great consideration of preserving so many lives, which may evidently arise from these different ways of having the disease, (for upon a general calculation, twenty-five or thirty die out of one hundred and fifty patients, having the distemper in the natural way, and one only out of this number, when inoculated,) it will appear, that this is a thing of very high importance; and that it is not easy to name an undertaking more laudable in itself, or more beneficial in its consequences, than the making a provision, that those, who really stand in the greatest need of this preservative, and yet from their low, though useful stations in life, are precluded from it, should be rescued from a condition, equally injurious to them and to society. But as the world will be often divided in sentiments, in matters of such a nature; so, by the constitution of this charity, due care is taken, that the intentions of such well disposed persons, as shall contribute to any branch of it, shall be punctually answered. For they may direct their benefactions to be bestowed upon such persons only, as are infected with the natural small-pox; or, if they judge the promoting inoculation the more beneficial, they may confine their gifts thereto; or, if given without any distinction, it will be applied to the general fund, both for natural small-pox and for inoculation.