I am free to confess that, overwhelming as is the evidence brought forward by Mr. Spencer in the articles already referred to, as showing that accidental variations, unguided by the helm of any main general principle which should as it were keep their heads straight, could never accumulate with the results supposed by Mr. Darwin; and overwhelming, again, as is the consideration that Mr. Spencer’s most crushing argument was allowed by Mr. Darwin to go without reply, still the considerations arising from the discoveries of the last forty years or so in connection with protoplasm, seem to me almost more overwhelming still. This evidence proceeds on different lines from that adduced by Mr. Spencer, but it points to the same conclusion, namely, that though luck will avail much if backed by cunning and experience, it is unavailing for any permanent result without them. There is an irony which seems almost always to attend on those who maintain that protoplasm is the only living substance which ere long points their conclusions the opposite way to that which they desire—in the very last direction, indeed, in which they of all people in the world would willingly see them pointed. It may be asked why I should have so strong an objection to seeing protoplasm as the only living substance, when I find this view so useful to me as tending to substantiate design—which I admit that I have as much and as seriously at heart as I can allow myself to have any matter which, after all, can so little affect daily conduct; I reply that it is no part of my business to inquire whether this or that makes for my pet theories or against them; my concern is to inquire whether or no it is borne out by facts, and I find the opinion that protoplasm is the one living substance unstable, inasmuch as it is an attempt to make a halt where no halt can be made. This is enough; but, furthermore, the fact that the protoplasmic parts of the body are _more_ living than the non-protoplasmic—which I cannot deny, without denying that it is any longer convenient to think of life and death at all—will answer my purpose to the full as well or better.