“The effects of this inhalation, as indicated by the patient’s own recollection,” says a writer in the _North British Review_, “are very various. In general they are somewhat as follows:--A pleasing sense of soothing succeeds the first irksomeness of the pungent vapour--a soothing of both mind and body. Ringing in the ears takes place, with some confusion of sight and intellectual perception. The limbs are felt cold and powerless; the hands and feet first, then the knees; and the feeling is as if these parts had ceased to be peculiar property, and dropped away. This sensation may gradually creep over the whole frame; the patient becoming, in more senses than one, truly etherealized; reduced to the condition of no body and all soul. The objects around are either lost sight of or strangely perverted; fancied shadows flit before the eyes, and then a dream sets in--sometimes calm and placid, sometimes active and bustling, sometimes very pleasurable, sometimes frightful, as a nightmare. Emerging, the figures and scenes shift rapidly, and grow fainter and fainter; present objects are caught by the eye once more, the ringing of the ears is heard again, consciousness and self-control return, a tendency to excited talking is very manifest, movement is unsteady, and, both in mind and body, a kind of intoxication is declared. It is, however, of a light and airy kind; very pure, very pleasant, and very passing, and, when gone, leaving very little trace behind. “Experience has fully shown that the brain may be acted on so as to annihilate, for the time, what may be termed the faculty of feeling pain; the organ of general sense may be lulled into profound sleep, while the organ of special sense, and the organ of intellectual function remain wide awake, active, and busily employed. The patient may feel no pain under very cruel cutting, and yet he may see, hear, taste, and smell, as well as ever, to all appearance; and he may also be perfectly conscious of everything within reach of his observation--able to reason on such events most lucidly, and able to retain both the events and the reasoning in his memory afterwards. We have seen a patient following the operator with her eyes most intelligently and watchfully, as he shifted his place near her, lifted his knife, and proceeded to use it; wincing not at all during its use; answering questions by gesture, very readily and plainly; and, after the operation was over, narrating every event as it occurred; declaring that she knew and saw all; stating that she knew and felt that she was being cut, and yet that she felt no pain whatever. Patients have said, quietly, ‘You are sawing now,’ during the use of the saw in amputation; and afterwards they have declared most solemnly, that though quite conscious of that part of the operation, yet they felt no pain. We have seen a patient enduring amputation of a limb without any sign of suffering, opening her eyes during the performance, at its most