{Footnote 20: Endoskopische Befunde bei Erkrankungen des Samenhugels Wein, 1880.} {Footnote 21: Bulletin Generales de Therapie, 1867, page 501.} {Footnote 22: Wiener Klinik, May, 1880.} {Footnote 23: Archives of Medicine, October, 1880, page 191.} STRICTURE THE RESULT OF MASTURBATION, AND THE CAUSE OF WEAKNESS AND IMPOTENCE. In brief it may be stated that +Masturbation+ in early life, and sexual excesses at a later period, may, and do produce +congestion+, +inflammation+, +spasm+, +ulceration+, +granulations+, +ulcers+, and both +spasmodic and organic strictures+ of the urethra; that +Spermatorrhoea+ and +Impotence+ are due to this condition, and that the only really rational treatment is that which directly medicates and heals these parts. This, +Civiale's Soluble Urethral Crayons+ do, better and quicker than anything else. Prof. GROSS,{24} for instance, says: "Exclusive of these cases, my notes show that 13 out of every 100 cases of stricture are due to Onanism;" and OTIS{25} says: "9 per cent. of all cases are traceable to that practice." REEVES, HENRY SMITH, GOULET, PHYSIC and LEROY give masturbation as a cause of stricture. BLACK states a like case leading to sexual incapacity, as a result of the stricture. WADE says: "In several instances of the kind, +where there had been no sexual intercourse+, the strictures, which were at the bulb, proved more than usually refractory from the extreme morbid sensitiveness of the whole urethral canal." Gross goes on to say, that in at least eight out of every ten cases of +Spermatorrhoea+ or +Impotence+, stricture of the urethra is the cause of the trouble, whether the stricture is due to gonorrhoea, gleet, etc., or to +masturbation or excesses+. {Footnote 24 _Op cit., page 25._} {Footnote 25: _Op cit._} THE CIVIALE PERFECTED AND COMBINED TREATMENT. How senseless, then, to endeavor to cure such conditions with stomach medicines. Still, the CIVIALE method does not wholly discard them. They have their place and their purpose, and served it well. It was his practice in many cases to use +Nervines+ and +Tonics+, as well as +Digestives+ and +Laxatives+, by the stomach, and with excellent results, for in many of these cases the +digestion was poor+, the +liver torpid+, the +bowels sluggish+ and +constipated+, and +filled with wind+, the +appetite capricious+ and +uneven+. +Crayons+ in the urethra could not wholly cure these symptoms, although they stopped the drain that originally caused them. Combined with the +Tonic-Regulator+, the results were prompt and satisfactory.