The formula used in preparing these Urethral Crayons is one of the finest the great +Civiale+ conceived. Repeated trials and modifications finally ended in an almost perfect remedy. Gleet or obstinate milky discharge or oozing of from two to twelve years' standing yielded painlessly and permanently to their use. Stricture, too, even when organic, if not so far advanced as to interfere seriously with urination, yielded kindly to this treatment, being gradually dissolved and absorbed until, at last, the canal was left free and clear, and all the symptoms of urinary irritation had disappeared. Testimony from Dr. Lorey, Interne at the _Hopital du Midi_, will give some idea of the popularity of this form of treatment in Paris. With them he cured eighty consecutive cases of Chronic Gleet. $5 Per Box. 2 Boxes, $8. 3 Boxes, $10. _COURSE No. 6._ _CIVIALE'S PRE-MARITAL TONIC COURSE._ This is the course we have already adverted to under the head of marriage, and we believe that enough was there said to make plain both its object and application. This, unlike the preceding courses, is, so to speak, a mixed one, consisting of a combination of (1) Tonics and Sexual Nervines to be taken by the mouth; (2) A Specially Prepared Course of Crayons (tonic, anti-spasmodic and detergent), to be used in the urethra, and (3) a lotion or application which, by being gently applied to the parts once a day with a sponge, soft cloth or the hand, adds greatly to the strength and erectile power, as well as the tone, development and vigor of the testicles. These are put up under the strict personal supervision of our head chemist, Mr. Du Bell, and are exactly in accordance with the formlae and instructions of the late Prof. Civiale. Price per Set, $25. This Course may be used alone or in connection with any of the other Courses. No man (or woman either) could be injured by it, and many weak and impotent sufferers will find in its use health, strength and bodily and mental vigor. In some instances the Tonic Regulator and Lotion part of this Course are advisable without the Crayons, and hence we quote their price separately. Tonic Regulator, $10. Lotio Fortior, $5. {Illustration: DR. LOREY, Interne at l'Hopital du Midi, Paris.} _CIVIALE'S TONIC-REGULATOR._ Civiale's Tonic-Regulator is all that its name indicates and much more besides. It is composed of Tonics, Nervines, Bitters, Laxatives, Nerve Foods, Cholagogues (acting on the Liver), Diuretics and Diaphoretics (remedies acting on the Kidneys and Skin and thereby increasing their secretions and cleansing and purifying the Blood), Digestives, etc., etc., etc. It will thus be seen that a more complete and uniform General Tonic-Regulator could not be devised, for it acts upon the Brain, Mind, Nervous System, Digestive Organs, Spleen and Pancreas, the Bowels (keeping them in a healthy and regular manner only--not purging or weakening), upon the Heart, Lungs, Skin, Blood and Kidneys.