Tomlinson_, aged twenty, who died, under the care of _Dr. Holme_, on the sixth day after a dose of _Corrosive Sublimate_. In this case, although an ounce of the mercurial salt had been swallowed, and the fluid ejected from the stomach was examined, only twelve hours afterwards, by _Drs. Henry_ and _Roget_, yet not the slightest trace of the poison could be detected! More recently we have received from the pen of _Mr. Alexander Murray_,[201] surgeon of Alford, some highly interesting cases of poisoning by Arsenic, and which are so illustrative of the present question, as well as several others that have fallen under consideration, that no apology can be necessary for introducing some account of them in this place. A family of the name of _Mitchell_, and which consisted of _William_, a robust man, aged 45, _James_, æt: 52, _Mary_, æt: 50, and _Helen_, æt: 48, breakfasted together on Sunday morning, (August 19, 1821) on porridge, consisting of milk, salt, and meal. _William_ partook largely, but _James_, who perceived “a sickening taste,” took less than common, while the sisters had their usual quantity. _William_ was seized with sickness shortly afterwards, about 10 _a. m._, on his way to church, and then with thirst and headache; and, on his return home, between three and four in the afternoon, he was seized with vomiting, which recurred often during the next four or five days, especially on his attempting to quench his thirst. In the early part of the week, he was heard to complain of pain in his stomach, eyes, throat, breast, and arms; he was observed to void his urine frequently; and about this time, he pointed out to one of his sisters a hollow[202] between his breast and belly, into which according to her expression, “she could have laid her arm.” His illness had scarcely at any time confined him to bed. On the evening of Friday, the 24th of August, he rode six miles, for the purpose of consulting _Mr. Murray_, the surgeon, and reporter of the cases; on Wednesday the 22d he had taken a dose of Epsom salts which operated, and at the time _Mr. Murray_ first saw him he complained of the following symptoms:—pain and heat in the region of the stomach and lower part of the chest; occasional uneasiness in the abdomen, and sometimes ineffectual efforts to go to stool; thirst; difficulty of breathing; heat and uneasiness of throat, with hoarseness; soreness of eyes, which had the common appearance of inflammation; shifting pains in his extremities, particularly the arms, which had not their usual strength; great restlessness; anxious expression of countenance; pulse frequent, 100-110, not strong.