A blister was applied over the stomach and lower part of the chest, and he took an opiate at bed time. On the following day, (Saturday 25th) _Mr. Murray_ visited him at his own house, and found him nearly as before, except that his countenance more strongly exhibited a disturbed and anxious expression, and the redness of the eyes, and the hoarseness were increased. _Mr. Murray_ also observed small roundish white accuminated prominences, on the palate and uvula, apparently as if the membrane covering the palate bones and _velum pendulum_, was detached at the parts by a whitish liquid. This day he took an ounce of castor oil, which operated in the afternoon, his illness was not observed to change during the evening, and he retired at about eight o’clock to rest. At a little past two in the morning, he rose in search of water to drink, and on returning to bed he was heard to utter a deep groan; after which he lay motionless and quiet, and very soon was found to have expired. The surgeon who saw the body, about 10 _a. m._, states that “_many bluish spots were observed on the inferior extremities_.” _James_, _Mary_, and _Helen Mitchell_ were attacked the same forenoon with their brother _William_, and with nearly similar symptoms; they were all, however, fortunate enough to recover, although a considerable period elapsed before their usual strength returned, and in all of them a numbness of the arms, or legs, occurred, together with a loss of muscular power. The body of _William Mitchell_ was, owing to particular circumstances, not opened until the 29th of August, (3 days 8 hours after death) when the following appearances presented themselves. “The face had a natural, composed appearance; and the rigidity of the body did not appear to be different from what is common. The right ear, and corresponding side of the face, as well as the scalp, exhibited a deep clay-blue colour. On the chest and belly, several spots and streaks, some green, others blue, were observed; and the back, upon which the body lay, was from head to foot of a livid colour; while several roundish spots, of a still deeper hue, gave to the shoulders and neck a mottled appearance. The penis was much swollen and red. The scrotum also was enlarged, and of a dark blue colour.