occasionally affected with a cancerous disease in the scrotum, somewhat similar to that which infests chimney sweepers. It is also singular that _Stahl_, in describing the putrescent tendency in the bodies of those who die from this poison, mentions in particular the gangrenous appearances of the parts of generation. The other organs of the body do not exhibit any particular appearances, which ought to be regarded as characteristic of death by arsenic; we must necessarily expect to find the traces of morbid action, especially where life has been unusually protracted; and the serous effusions found in the body of _William Mitchell_, are to be referred to such a cause. _Mr. Brodie_ has stated that, in animals killed by arsenic, the blood is usually found fluid in the heart and vessels after death; this agrees with the observation of _Ruysch_, who says that he never found the blood coagulated in the human body, after death occasioned by this poison; as well as with that of _Dr. Jaeger_, who describes the cavities of the heart, especially of the right side, to be, upon these occasions, turgid with blood, but that coagula are very seldom found in them. A question, of a very considerable importance in a forensic point of view, has arisen with respect to the means, by which we may distinguish whether arsenic, found in the body, had been introduced into the digestive canal during life, or after death. In general, this fact is placed beyond suspicion by the testimony of those to whose care the body had been confided, previous to dissection. But cases have occurred where a poisonous substance has been introduced into the rectum of a dead body, with the diabolical intention of accusing an innocent person of having been the perpetrator of the poisoning. We are not aware of any English case of this kind, but _M. Orfila_ states that in the proceedings of the Criminal Court of Stockholm such a case stands recorded. Fortunately there would not be much difficulty in detecting the crime; for were the arsenic applied to the rectum after death, the change of structure would not extend beyond the part in actual contact with it, but would be distinctly separated from the rest of the intestine _by a well defined line of demarcation_, which can never happen where the arsenic has acted during life; for, in this latter case, the transition from the diseased to the healthy structure will be gradual, and the limits of each imperceptible.