the heart has ceased, its motions are continued. The experiment may also be very satisfactorily varied in the following manner; apply a ligature to the carotid arteries in the neck, so as to prevent the occurrence of hemorrhage, and then decapitate the animal; if respiration be now artificially maintained, the heart will suffer no disturbance in its motions, but the circulation will be preserved for several hours in the body of the decapitated animal. In further illustration of this view of the subject, _Mr. Brodie_ observes, that many reptiles which are capable of respiring by means of the skin, will survive the loss of the brain for so long a period, that the wound made by decapitation, becomes cicatrized, and death only takes place at last in consequence of inanition.—(_Manuscript Notes._) In farther illustration of these views, let us observe the mode in which death takes place in apoplexy, or in cases of pressure on the brain, whether occasioned by a depressed portion of bone, or by blood extravasated within the cranium. At first the patient is insensible to all external impressions, but the breathing is not affected; after an interval, however, the respiration becomes difficult and laborious, and the purple hue of the lips and cheeks, from the sub-cutaneous vessels, demonstrates that the blood is imperfectly oxygenized. The arterial action becomes more slow, in proportion only as the respiration is more difficult; and the pulse may even be distinguished at the wrist, after the breathing has altogether ceased; under such circumstances it is obvious that life might be protracted for several hours by artificial inflation of the lungs, but as no ultimate benefit could be derived from such an operation, its expediency may be fairly questioned.