In the treatment of this disease, the first indication was, to clear the primæ viæ. Some gentlemen exhibited emetics; but in general there was no time for this. The general practice at last was, to begin by giving a purge of calomel, and the general remark was, that, if it operated briskly, the head was relieved and the skin became soft. The second indication most generally agreed upon, was the inducing ptyalism and perspiration. As offering the fairest prospect of effecting both at once, Mr Price proposed using the warm nitric-acid bath, but unfortunately our stock of nitric-acid was insufficient to do this, otherwise than on a small scale. Mr Price got a little of the acid at El Hammed; but, from circumstances there, he could not always have the warm bath; however, he writes, “On three of my patients, whose gums I could not readily affect with mercury, I determined to try the nitric-acid bath: it has shewn wonderful effects, ptyalism has been produced in all the three; but the cold has regularly induced rigors and severe attacks of fever, and I shall loose my patients.” Nitric acid was given internally; and, where the patients would drink it, it shewed good effects. Mr O’Farrel, at Aboukir, succeeded in making three dragoons take it much diluted as their common drink; and they did well all of them. Mr Price thought well of citric acid. In some of the Arabs he effected cures by this, and by a bath of strong vinegar. Both Mr Rice and Mr Price were in the habit of washing their patients with vinegar and sponging them with it, as strong as it could be procured, or with lime-juice. They dipped rags in the acids, and kept them constantly applied to the buboes. The head and stomach were relieved by wet cloths being kept to the scrotum. The third indication was, to obviate the debility which appeared always to be very great. With this view, bark, wine, and opium, were very largely given; and, at a certain stage, the cold bath.