"The biting of a wood-hound is deadly and venomous, and such venom is perilous. For it is long hidden and unknown, and increaseth and multiplieth itself, and is sometimes unknown to the year's end, and then the same day and hour of the biting it cometh to the head, and breedeth frenzy. They that are bitten of a wood-hound have in their sleep dreadful sights, and are fearful, astonished, and wroth without cause. And they dread to be seen of other men, and bark as hounds, and they dread water most of all things, and are afeared thereof, full sore and squeamous also. Against the biting of a wood-hound wise men and ready use to make the wounds bleed with fire or with iron, that the venom may come out with the blood that cometh out of the wound." A very interesting development of therapeutics in the Middle Ages was the employment of the red light treatment to shorten the course and the severity of the fever in smallpox, and above all to prevent pitting; it was employed successfully by John of Gaddesden in the case of the son of King Edward II. Recent investigation by Cholmeley has shown that both Gilbertus Anglicus (1290) and Bernard de Gordon (1305) antedated John of Gaddesden in references to the red light treatment. All of these men were professors at Montpellier, showing that the medical school of the South of France was a rival in the use of natural methods of cure to its better-known predecessor of Southern Italy. Curiously enough, the "Rosa Anglica" of Gaddesden, in which the reference to the red light is made, is deservedly characterized by Garrison as "a farrago of Arabist quackeries and countrified superstitions"; it well deserves Guy de Chauliac's bitter criticism of it as "a scentless rose."