Nicaise, in the Introduction to his edition of Guy de Chauliac's "Grande Chirurgie" (Paris, 1893), has a brief review of the history of women in medicine, with special reference to France. He supplies practically all the information available in very short compass, as well as the references where more details can be obtained. "Women continued to practise medicine in Italy for centuries, and the names of some who attained great renown have been preserved for us. Their works are still quoted from in the fifteenth century. "There was none of them in France who became distinguished, but women could practise medicine in certain towns at least on condition of passing an examination before regularly appointed masters. An edict of 1311, at the same time that it interdicts unauthorized women from practising surgery, recognizes their rights to practise the art if they have undergone an examination before the regularly appointed master surgeons of the corporation of Paris. An edict of King John, April, 1352, contains the same expressions as the previous edict. Du Bouley, in his 'History of the University of Paris' gives another edict by the same king, also published in the year 1352, as a result of the complaints of the faculties at Paris, in which there is also question of women physicians. This responded to a petition: 'Having heard the petition of the Dean and Masters of the Faculty of Medicine at the University of Paris, who declare that there are very many of both sexes, some of the women with legal title to practise and some of them merely old pretenders to a knowledge of medicine, who come to Paris in order to practise, be it enacted,' etc. (The edict then proceeds to repeat the terms of previous legislation in this matter.) "Guy de Chauliac speaks also of women who practised surgery. They formed the fifth and last class of operators in his time. He complains that they are accustomed to too great an extent to give over patients suffering from all kinds of maladies to the will of Heaven, founding their practice on the maxim, 'The Lord has given as he has pleased; the Lord will take away when he pleases; may the name of the Lord be blessed.' "In the sixteenth century, according to Pasquier, the practice of medicine by women almost entirely disappeared. The number of women physicians becomes more and more rare in the following centuries, just in proportion as we approach our own time. Pasquier says that we find a certain number of them anxious for knowledge, and with a special penchant for the study of the natural sciences and even of medicine, but very few of them take up practice."