Mendel's principles of heredity: A defenceMendel, Gregor
Science
Mendel's principles of heredity: A defence
Mendel, Gregor
Heredity; Hybridization; Mendel's law; Weldon, Walter Frank Raphael. Mendel's laws of alternative inheritance in peas
If however instead of pure extreme varieties we were to take a pair of
varieties differing normally by only a foot or two, we might, owing
to the masking effects of conditions, &c., have great difficulty in
distinguishing the three forms in the second generation. There would
besides be twice as many heterozygous individuals as homozygous
individuals of each kind, giving a symmetrical distribution of
heights, and who might not--in pre-Mendelian days--have accepted such
evidence--made still less clear by influence of conditions--as proof of
Continuous Variation both of zygotes and gametes?
Suppose, then, that instead of two pure types, we had six or eight
breeding together, each pair forming their own heterozygote, there
would be a very remote chance of such purity or fixity of type whether
of gamete or zygote being detected.
_Dominance_, as we have seen, is merely a phenomenon incidental to
specific cases, between which no other common property has yet been
perceived. In the phenomena of _blended_ inheritance we clearly have no
dominance. In the cases of _alternative_ inheritance studied by Galton
and Pearson there is evidently no _universal_ dominance. From the
tables of Basset hound pedigrees there is clearly no definite dominance
of either of the coat-colours. In the case of eye-colour the published
tables do not, so far as I have discovered, furnish the material for a
decision, though it is scarcely possible the phenomenon, even if only
occasional, could have been overlooked. We must take it, then, there is
no sensible dominance in these cases; but whether there is or is not
sensible gametic purity is an altogether different question, which,
so far as I can judge, is as yet untouched. It may perfectly well be
that we shall be compelled to recognize that in many cases there is no
such purity, and that the characters may be carried by the gametes
in any proportion from zero to totality, just as some substances may
be carried in a solution in any proportion from zero to saturation
without discontinuous change of properties. That this will be found
true in _some_ cases is, on any hypothesis, certain; but to prove the
fact for any given case will be an exceedingly difficult operation, and
I scarcely think it has been yet carried through in such a way as to
leave no room for doubt.
Conversely, the _absolute_ and _universal_ purity of the gametes has
certainly not yet been determined for any case; not even in those
cases where it looks most likely that such universal purity exists.
Impairment of such purity we may conceive either to occur in the form
of mosaic gametes, or of gametes with blended properties. On analogy
and from direct evidence we have every right to believe that gametes
of both these classes may occur in rare and exceptional cases, of as
yet unexplored nature[21], but such a phenomenon will not diminish the
significance of observed purity.
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