Mendelism: Third EditionPunnett, Reginald Crundall
Science
Mendelism: Third Edition
Punnett, Reginald Crundall
Mendel's law
The points with which the breeder is concerned are often fine ones, not
very evident except to the practised eye. Between an ordinary Dutch rabbit
and a winner, or between the comb of a Hamburgh that is fit to show and one
that is not, the differences are not very apparent to the uninitiated.
Whether Mendelism will assist the breeder in the production of these finer
points is at present doubtful. It may be that these small differences are
heritable, such as those that form the basis of Johannsen's pure lines. In
this case the breeder's outlook is {169} hopeful. But it may be that the
variations which he seeks to perpetuate are of the nature of fluctuations,
dependent upon the earlier life conditions of the individual, and not upon
the constitution of the gametes by which it was formed. If such is the
case, he will get no help from the science of heredity, for we know of no
evidence which might lead us to suppose that variations of this sort can
ever become fixed and heritable.
* * * * *
{170}
CHAPTER XV
MAN
[Illustration: FIG. 32.
Normal and brachydactylous hands placed together for comparison. (From
Drinkwater.)]
[Illustration: FIG. 33.
Radiograph of a brachydactylous hand.]
Though the interest attaching to heredity in man is more widespread than in
other animals, it is far more difficult to obtain evidence that is both
complete and accurate. The species is one in which the differentiating
characters separating individual from individual are very numerous, while
the number of the offspring is comparatively few, and the generations are
far between. For these reasons, even if it were possible, direct
experimental work with man would be likely to prove both tedious and
expensive. There is, however, another method besides the direct one from
which something can be learned. This consists in collecting all the
evidence possible, arranging it in the form of pedigrees, and comparing it
with standard cases already worked out in animals and plants. In this way
it has been possible to demonstrate in man the existence of several
characters showing simple Mendelian inheritance. As few besides medical men
have hitherto been concerned practically with heredity, such records as
exist are, for the most part, records of deformity or of disease. So it
happens that most of the {171} pedigrees at present available deal with
characters which are usually classed as abnormal. In some of these the
inheritance is clearly Mendelian. One of the cases which has been most
fully worked out is that of a deformity known as brachydactyly. In
brachydactylous people the {172} whole of the body is much stunted, and the
fingers and toes appear to have two joints only instead of three (cf. Figs.
32 and 33). The inheritance of this peculiarity has been carefully
investigated by Dr. Drinkwater, who collected all the data he was able to
find among the members of a large family in which it occurred. The result
is the pedigree shown on p. 173.
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